Logistic regression models assessed the associations of RHR with cognitive function, and linear regression models estimated the associations with hippocampal subfield volume and white matter tract integrity indexed by magnetic resonance imaging data. Cox regression and restricted cubic spline models examined the associations between RHR with all-cause dementia (ACD) and its major subtypes-Alzheimer’s disease (AD) and vascular dementia (VaD). Three hundred thirty-nine thousand nine hundred one participants with no prior diagnosis of dementia from the UK biobank were analyzed. This study aims to investigate the relationships of RHR with different dementia types, cognitive function, and brain structural abnormalities. However, evidence characterizing the associations of RHR with different dementia subtypes and their underlying mechanisms remains scarce. ![]() Resting heart rate (RHR) has been linked with an increased risk of dementia.
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